cb1 antagonist 1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10510	CB1 antagonist 1		Cannabinoid Receptor
	CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, and gastrointestinal disorders, psychosis, and cardiovascular.		Cannabinoid Receptor
T14881	CB1 antagonist 2	AM4113	Cannabinoid Receptor
	CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.		Cannabinoid Receptor
T5996	CB1-IN-1	DBPR211	Cannabinoid Receptor
	CB1-IN-1 (DBPR211) is a peripherally restricted CB1R antagonist, for CB1R and CB2R with Ki of 0.3 nM and 21 nM,respectively.		Cannabinoid Receptor
T41350	6-Bromopravadoline	WIN 54461	Cannabinoid Receptor
	6-Bromopravadoline (WIN 54461) (WIN 54461) is an antagonist of CB1. 6-Bromopravadoline acts as an inhibitor of the binding of [3H]Win 55212-2 (IC 50 =515 nM) reflective of cannabinoid receptor binding [1] [2].		Cannabinoid Receptor
T1519	Rimonabant hydrochloride	SR 151716A,SR 141716A	Cannabinoid Receptor , Antibacterial
	Rimonabant hydrochloride (SR 141716A) is a cannabinoid receptor antagonist, binding selectively to central cannabinoid receptors (CB1) with high affinity.		Cannabinoid Receptor , Antibacterial
T8511	TM38837		Cannabinoid Receptor
	TM38837 is an antagonist of cannabinoid receptor type 1 (CB1), with potential for the treatment of obesity and type 2 diabetes.		Cannabinoid Receptor
T1915	AM251		Cannabinoid Receptor , GPR
	AM251 is a effective CB1 receptor antagonist (IC50/Ki: 8 /7.49 nM) that displays 306-fold selectivity over CB2 receptors; also effective GPR55 agonist (EC50: 39 nM).		Cannabinoid Receptor , GPR
TN5131	Tetrahydrocannabivarin	THCV,delta9-Tetrahydrocannabivarin,CRM,Tetrahydrocannavarin	Cannabinoid Receptor
	Tetrahydrocannabivarin (CRM) is a neutral cannabis receptor subtype (CB1) receptor antagonist, it can increases neural responding to rewarding and aversive stimuli, this effect profile suggests therapeutic activity in ob...		Cannabinoid Receptor
T13081	Taranabant racemate	MK-0364 racemate	Cannabinoid Receptor
	Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor.		Cannabinoid Receptor
T83533	(R)-Monlunabant	(R)-MRI-1891	Cannabinoid Receptor
	(R)-Monlunabant ((R)-MRI-1891) serves as a CB1 receptor antagonist utilized in obesity and metabolic disease research [1].		Cannabinoid Receptor
T22140	(R)-SLV 319
	(R)-SLV 319 is a potent and selective antagonist of cannabinoid receptor 1 (CB1), with a K i value of 894 nM. (R)-SLV 319 is a dextrorotatory counterpart of SLV 319 [1]
T21914	(S)-SLV 319
	Ibipinabant (SLV319) is a potent, selective, and orally active antagonist of the cannabinoid CB1 receptor, demonstrating a K i of 7.8 nM and exhibiting over 1000-fold selectivity for CB1 compared to CB2 (K i =7943 nM). I...
T78674	Isopropyl dodec-11-enylfluorophosphonate	IDEFP	FAAH
	Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibits equipotent inhibition of fatty acid amide hydrolase (FAAH), with b...		FAAH
T21811	LH 21
	LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats., and results in a dose-dependent inhibition of feeding [1].
T36591	ABD459
	ABD459 is a neutral antagonist of the central cannabinoid 1 (CB1) receptor (Ki = 8.6 nM). It inhibits food consumption in nonfasted mice without affecting motor activity. ABD459 reduces active food seeking for 5-6 hours ...
T23099	O-2050		Others
	O-2050 is a high affinity cannabinoid CB 1 receptor antagonist with a K i of 2.5 nM. O-2050 inhibits cannabinoid CB 2 receptor with Ki of 0.2 nM. O-2050 decreased food intake in mice and caused locomotor stimulation in m...		Others